GABAPENTIN ENACARBIL Drug Record

  • GABAPENTIN ENACARBIL chembl:CHEMBL1628502 Approved

    Alternate Names:

    ASP8825
    HORIZANT
    GSK1838262
    GABAPENTIN ENACARBIL
    XP-13512
    XP 13512
    GABAPENTIN ENCARBIL
    ASP-8825
    GABAPENTINA ENACARBILO
    REGNITE®
    GABAPENTINE ENACARBIL
    GABAPENTINUM ENACARBILUM
    XP13512
    HORIZANT®
    drugbank:08872
    chemidplus:478296-72-9
    rxcui:1101333
    chembl:CHEMBL1628502
    pubchem.compound:9883933

    Drug Info:

    FDA Approval not approved
    Drug Class small molecule
    Drug Indications for treatment of restless legs syndrome
    (0 More Sources)

    Publications:

  • GABAPENTIN ENACARBIL   CACNA2D2

    Interaction Score: 0.49

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Trial Name XP13512
    Novel drug target Established target
    Mechanism of Interaction Voltage-gated calcium channel modulator

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNG6

    Interaction Score: 0.41

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNG4

    Interaction Score: 0.41

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNG5

    Interaction Score: 0.41

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNG7

    Interaction Score: 0.41

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Voltage-gated calcium channel modulator

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNG3

    Interaction Score: 0.41

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Voltage-gated calcium channel modulator

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNA2D3

    Interaction Score: 0.35

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNG2

    Interaction Score: 0.35

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNA2D4

    Interaction Score: 0.35

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Voltage-gated calcium channel modulator

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNA1E

    Interaction Score: 0.31

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Voltage-gated calcium channel modulator

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNB3

    Interaction Score: 0.27

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNA2D1

    Interaction Score: 0.27

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes
    Trial Name XP13512

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNB1

    Interaction Score: 0.27

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Voltage-gated calcium channel modulator

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNB4

    Interaction Score: 0.27

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Voltage-gated calcium channel modulator

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNB2

    Interaction Score: 0.25

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNA1A

    Interaction Score: 0.22

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNG1

    Interaction Score: 0.19

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNA1B

    Interaction Score: 0.18

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes
    Trial Name XP13512

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNA1I

    Interaction Score: 0.15

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Voltage-gated calcium channel modulator

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNA1G

    Interaction Score: 0.15

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNA1F

    Interaction Score: 0.11

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNA1D

    Interaction Score: 0.1

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNA1H

    Interaction Score: 0.09

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNA1C

    Interaction Score: 0.08

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Mechanism of Interaction Voltage-gated calcium channel modulator
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • GABAPENTIN ENACARBIL   CACNA1S

    Interaction Score: 0.08

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Voltage-gated calcium channel modulator

    PMIDs:
    None found


    Sources:
    ChemblInteractions